Description
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Generic Name: Oxycodone and acetaminophen
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Brand Name: Percocet
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Drug Class: Analgesics, Opioid Combos
HOME DRUGS A-Z LIST OF SIDE EFFECTS DRUG CENTER PERCOCET (OXYCODONE AND ACETAMINOPHEN) DRUG
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Description of the drug
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Dosage and indications for use
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Effects on the body
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Interactions between drugs
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A few warnings
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Take precautions.
Drug Description
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Percocet may cause other side effects in addition to those listed here. Ask your doctor or pharmacist for more information.
WARNING
Hepatotoxicity
Acetaminophen has been associated with acute liver failure, requiring liver transplants and sometimes leading to death. Buy Percocet Online
DESCRIPTION
Each tablet, for oral administration, contains oxycodone hydrochloride and acetaminophen in the following strengths:
All strengths of PERCOCET also have the following inactive ingredients: Colloidal silicon dioxide, croscarmellose sodium, crospovidone, microcrystalline cellulose, povidone, pregelatinized cornstarch, and stearic acid. Further, the 2.5 mg/325 mg strength contains the dye FD&C Red No. This formulation contains FD&C Blue No. 325 and Aluminum Lake 40 at 5 mg/325 mg strength. 1 Aluminum lake. FD&C Yellow No. 6 Aluminum Lake is available in the strength of 7.5 mg/325 mg. D&C Yellow No.
Oxycodone is a semisynthetic opioid analgesic that appears as a white, odorless, crystalline powder with a saline, bitter taste. The molecular formula for oxycodone hydrochloride is C18H21NO4•HCl and the molecular weight is 351.82.
SIDE EFFECTS
- PERCOCET tablets may cause respiratory depression, apnea, respiratory arrest, circulatory depression, hypotension, and shock (see OVERDOSAGE).
Additionally, the drug may cause euphoria, dysphoria, constipation, and pruritus.
The following hematologic reactions may occur: thrombocytopenia, neutropenia, pancytopenia, hemolytic anemia. Acetaminophen has also been associated with rare cases of agranulocytosis. A dose-dependent, potentially fatal hepatic necrosis occurs at high doses. Hypoglycemic coma and renal tubular necrosis are also possible.
As a result of postmarketing experiences with PERCOCET tablets, the following adverse reactions were reported by organ system and in decreasing order of severity and/or frequency:
The whole body
In addition to anaphylactic reactions, allergic reactions, malaise, asthenia, fatigue, chest pains, fevers, hypothermia, thirst, headaches, excessive sweating, accidental overdoses, non-accidental overdoses can take place.
Cardiovascular
Hypotension, hypertension, tachycardia, orthostatic hypotension, bradycardia, palpitations, dysrhythmias Buy Percocet Online
WARNINGS
Misuse, Abuse, and Diversion of Opioids
As with other opioid agonists, Oxycodone can also be abused. If the physician or pharmacist is concerned about an increased risk of misuse, abuse, or diversion, they should consider this when prescribing or dispensing PERCOCET tablets. Pain management should not be hindered by concerns about misuse, addiction, and diversion.
In order to prevent and detect abuse or diversion of this product, healthcare professionals should contact their State Professional Licensing Board or State Controlled Substances Authority.
There are a number of potentially serious adverse reactions and complications associated with the administration of PERCOCET (Oxycodone and Acetaminophen Tablets, USP): Buy Percocet Online
PRECAUTIONS
General
It is recommended that opioid analgesics be used cautiously when combined with CNS depressants. This is because the benefits of opioid analgesia outweigh the risks of respiratory depression, altered mental state, and postural hypotension.
Acute abdominal conditions
It is recommended that opioid analgesics be used cautiously when combined with CNS depressants. This is because the benefits of opioid analgesia outweigh the risks of respiratory depression, altered mental state, and postural hypotension.
OVERDOSE
An acute overdose of oxycodone or acetaminophen may result in toxicity. Buy Percocet Online
The signs and symptoms of the disease
An overdose of acetaminophen can cause dose-dependent and potentially fatal hepatic necrosis. It is also possible to develop renal tubular necrosis, hypoglycemic coma, and coagulation defects.
Hepatic toxicity may not become apparent for 48 to 72 hours following ingestion.
CLINICAL PHARMACOLOGY
Central Nervous System
Oxycodone is a semisynthetic pure opioid agonist whose principal therapeutic action is analgesia. Oxycodone also has anxiolytic, euphoria, and relaxation effects. As a result, endorphins and enkephalins, endogenous opioid-like compounds, mediate these effects. Buy Percocet Online
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